Adderall is a medication for people with attention deficit hyperactivity disorder (ADHD) and narcolepsy. It contains both dextroamphetamine and amphetamines. There are many forms of Adderall, including immediate-release and extended-release. Depending on which formulation you choose, the effects of Adderall will vary. We wanted to find out how long Adderall can last in your body because it is one of America’s most popular ADHD medications.

What is the average time it takes for Adderall’s effects to kick in?

The formulation of Adderall you choose will determine how long it takes to kick in. The name of immediate-release Adderall is because it kicks in usually within 30 minutes. Extended-release Adderall can take up to an hour for it to kick in. Side effects may last as long as 12 hours.

Because side effects last only four to six hours, it can take immediate-release Adderall multiple times per day. Adderall XR can be used by people who need to take the medication for a long time and may require daily doses. They may only take one capsule per day.

No matter what form Adderall takes, it improves ADHD symptoms by increasing brain norepinephrine and brain dopamine levels. Dopamine, and norepinephrine, both naturally occurring chemicals, have different functions. Dopamine is involved in emotion and mood, but norepinephrine affects physiological responses such as breathing and heart rate.

Adderall is effective in treating ADHD symptoms such as poor concentration, focus, hyperactivity, and impulsivity; it can also cause side effects such as:

Other side effects include mood swings and thoughts of suicide, unusual wounds or toes, coldness, numbness in the extremities, teeth grinding, and mood swings. If you have any of these symptoms, you must immediately contact your doctor or seek medical assistance.

Adderall is a popular stimulant because it affects norepinephrine and dopamine. It’s abuse includes:

  • Taking larger doses of the drug than prescribed.
  • Crushing and snorting it.
  • Using it with alcohol or drugs.
  • Even taking it without a prescription.

It’s abuse is dangerous because of its addictiveness. Overdose and dependence are also possible.

How long does Adderall stay in your system?

Adderall is absorbed into the gastrointestinal tract, broken down by the liver, and eliminated from the body in the urine. About 20% to 25% of Adderall is converted into metabolites. These traces are detectable in drug screenings or drug tests. Adderall can be removed by urine, but the drug remains active in the body. There are many ways to detect Adderall.

How long Adderall lasts in your body is determined by its half-life. Adderall’s half-life can last between 9-14 hours, depending on the formula. Half the drug can take between 9 and 14 hours to be removed from the body. Adderall lasts for three days or 72 hours in the body. People worried about Withdrawal symptoms, Drug tests, or drug testing may want to know how long it takes for Adderall to be eliminated from the body.

How fast does it leave your body?

Adderall is absorbed through the gastrointestinal tract. Your urine then breaks down Adderall.

The urine excretes Adderall. However, it acts throughout your body so that you can detect it in many ways.


A blood test can detect Adderall up to 46 hours following last use. Adderall can be seen most quickly by blood tests after it has been taken.


Adderall can be detected in the urine between 48 and 72 hours after last use. Because Adderall is excreted through urine, this test will typically show a higher level than other drug tests.


Adderall can still be detected in saliva between 20 and 50 hours after last use.


Although drug testing with hair may not be a popular method for Adderall, it can detect Adderall up to 3 Months Trusted Source after the last use.

How long can it stay in your body?

Different bodies break down, metabolize and eliminate Adderall at different rates. Many factors can affect the time Adderall remains in your body after it is metabolized.

Body composition

Adderall’s duration of stay in your system can be affected by your body composition, including weight, body fat, height, and overall body weight. Also, because people with larger bodies require higher medication doses, it will take longer to get rid of their bodies.

However, evidence from a trusted source that drugs such as Adderall metabolized through a specific liver pathway will be cleared from the body quicker in those with more body fat.


Everybody has enzymes in the liver that help to metabolize or break down drugs like Adderall. Everything can affect your metabolism, from your activity level, gender, and other medications.

The time a drug remains in your body depends on how fast it is metabolized.


There are many strengths of Adderall, from capsules or tablets containing 5 mg to 30mg capsules containing Adderall. It takes longer for your body to absorb Adderall if you take a higher dose fully because higher doses of Adderall will remain in your body for longer.

However, they dissolve in your body at different rates, which can impact the length of time that the medication remains in your body.


It can take longer for medication to reach your system as you age. There are many reasons for this.

  • As you age, your liver size decreases. It may take longer for Adderall to be wholly broken down in your liver.
  • As we age, our urine output decreases. Age-related conditions such as heart disease and ageing can also cause kidney function to decline. These factors can lead to medications staying in your body longer.
  • As you age, your body composition changes. Which can affect how quickly your body processes and eliminates drugs.

Organ function

Adderall can be absorbed through the gastrointestinal tract. The liver then processes it and flushes it out through the kidneys. Adderall may take longer to leave your body if any of these organs and systems are not working correctly.

What is the working principle of Adderall?

Although it may seem counterintuitive, Adderall stimulates the central nervous system.

ADHD patients may not have enough dopamine to stimulate their frontal brain. It is thought to be the brain’s “reward centre.” As a result, they may become impulsive, thrill-seeking, or easily distracted.

Adderall stimulates the central nervous system and boosts dopamine levels in the frontal brain. As a result, people with ADHD can stop looking for stimulation, which helps them focus better.

The bottom line

Depending on the type of detection test used, Adderall can still be detected in your system up to 72 hours or three days after you last used it. Adderall may help with ADHD. Narcolepsy symptoms when prescribed by a doctor.

Many factors affect the time that medication remains in your body, such as dosage, metabolism rate, age, organ function, etc.


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